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Fat burners for women: Benefits and side effects. It's important to note that the Mayo Clinic Diet was designed for general weight loss. People who have a specific health condition or who aren't sure how to adapt the diet to their lifestyle should work with their healthcare team. For example, if you have diabetes, heart disease, or kidney disease, your dietary requirements are going to be slightly different. Your doctor or a registered dietitian can help you make changes as needed.

Another frontier scientists are exploring is how the microbiome-the trillions of bacteria that live inside and on the surface of the human body-may be influencing how the body metabolizes certain foods. Dr. Eran Elinav and Eran Segal, researchers for the Personalized Nutrition Project at the Weizmann Institute of Science in Israel, believe the variation in diet success may lie in the way people's microbiomes react to different foods.

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